C1GALT1C1 Antibody

Catalog Number:

46366

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q96EU7
NCBI Gene ID:29071
NCBI Protein:BC011930

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic protein corresponding to residues near the C terminal of human C1GALT1C1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total C1GALT1C1 protein.

Applications:

IHC

Background:

This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

References:

appl_detail:

Immunohistochemistry: 1: 50-300

Datasheet PDF