Product Datasheet
C1GALT1C1 Antibody
Catalog Number: 46366
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q96EU7
NCBI Gene ID:29071
NCBI Protein:BC011930
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the C terminal of human C1GALT1C1
- appl_detail:
Immunohistochemistry: 1: 50-300
- other_names:
- TNPS; COSMC; MST143; C1GALT2; HSPC067; C38H2-L1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total C1GALT1C1 protein.
- Background:
- This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
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