1-832-868-1888
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Catalog Number: |
46359 |
| other_names: | G10; EDG2; Cwc14; EDG-2; fSAP17; YCR063W |
Amount: |
100μg |
| calculated_mw: | 17 kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot:P41223 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Full length fusion protein of human BUD31 |
Purification: |
Antigen affinity purification |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total BUD31 protein. |
Applications: |
WB IHC |
Background: |
BUD31 (Protein G10 homolog, EDG-2) is a 144 amino acid protein encoded by the human gene BUD31. BUD31 is a nuclear protein that belongs to the BUD31 (G10) family. BUD31 is found on chromosome 7 which is about 158 milllion bases long, encodes over 1,000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the long (q) arm of human chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. |
References: |
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appl_detail: |
Western blotting: 1:1000-1:5000 |
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