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BUD31 Antibody

Catalog Number:

46359
other_names: G10; EDG2; Cwc14; EDG-2; fSAP17; YCR063W

Amount:

100μg
calculated_mw: 17 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:P41223
NCBI Gene ID:8896
NCBI Protein:BC022821

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human BUD31

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total BUD31 protein.

Applications:

WB IHC

Background:

BUD31 (Protein G10 homolog, EDG-2) is a 144 amino acid protein encoded by the human gene BUD31. BUD31 is a nuclear protein that belongs to the BUD31 (G10) family. BUD31 is found on chromosome 7 which is about 158 milllion bases long, encodes over 1,000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the long (q) arm of human chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1: 50-300

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