Product Datasheet
BUD31 Antibody
Catalog Number: 46359
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P41223
NCBI Gene ID:8896
NCBI Protein:BC022821
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human BUD31
- appl_detail:
- Western blotting: 1:1000-1:5000
Immunohistochemistry: 1: 50-300
- other_names:
- G10; EDG2; Cwc14; EDG-2; fSAP17; YCR063W
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total BUD31 protein.
- Background:
- BUD31 (Protein G10 homolog, EDG-2) is a 144 amino acid protein encoded by the human gene BUD31. BUD31 is a nuclear protein that belongs to the BUD31 (G10) family. BUD31 is found on chromosome 7 which is about 158 milllion bases long, encodes over 1,000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the long (q) arm of human chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
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