CD276 Antibody

Catalog Number:

46434

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q5ZPR3
NCBI Gene ID:80381
NCBI Protein:NP_001019907

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human CD276

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total CD276 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 25-100

Datasheet PDF