UNC5B Antibody

Catalog Number:

43988

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8IZJ1
NCBI Gene ID: 219699

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human UNC5B

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total UNC5B protein.

Applications:

IHC

Background:

This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF