Product Datasheet
UNC5B Antibody
Catalog Number: 43988
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8IZJ1
NCBI Gene ID: 219699
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human UNC5B
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- UNC5H2; p53RDL1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total UNC5B protein.
- Background:
- This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.
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