WEE2 Antibody

Catalog Number:

43978

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P0C1S8
NCBI Gene ID: 494551

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human WEE2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total WEE2 protein.

Applications:

IHC

Background:

Wee 2 (Wee1-like protein kinase 2), also known as WEE1B, is a 567 amino acid nuclear protein belonging to the protein kinase superfamily. Expressed in testis, Wee 2 phosphorylates and inhibits Cdc2 and may act as a negative regulator of entry into the G2 to M transition of mitosis. The gene encoding Wee 2 is located on human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF