Product Datasheet  
WEE2 Antibody  
Catalog Number: 43978  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P0C1S8
    NCBI Gene ID: 494551
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide of human WEE2
  • reactivity:  
  • Hu
  • appl_detail:  

  • Immunohistochemistry: 1: 20-100
  • other_names:  
  • WEE1B
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total WEE2 protein.
  • Applications:  
  • IHC
  • Background:  
  • Wee 2 (Wee1-like protein kinase 2), also known as WEE1B, is a 567 amino acid nuclear protein belonging to the protein kinase superfamily. Expressed in testis, Wee 2 phosphorylates and inhibits Cdc2 and may act as a negative regulator of entry into the G2 to M transition of mitosis. The gene encoding Wee 2 is located on human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.



 
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