Product Datasheet
WEE2 Antibody
Catalog Number: 43978
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P0C1S8
NCBI Gene ID: 494551
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human WEE2
- appl_detail:
Immunohistochemistry: 1: 20-100
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total WEE2 protein.
- Background:
- Wee 2 (Wee1-like protein kinase 2), also known as WEE1B, is a 567 amino acid nuclear protein belonging to the protein kinase superfamily. Expressed in testis, Wee 2 phosphorylates and inhibits Cdc2 and may act as a negative regulator of entry into the G2 to M transition of mitosis. The gene encoding Wee 2 is located on human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
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