WDR11 Antibody

Catalog Number:

43976

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BZH6
NCBI Gene ID: 55717

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human WDR11

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total WDR11 protein.

Applications:

IHC WB

Background:

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100

Datasheet PDF