Product Datasheet
WDR11 Antibody
Catalog Number: 43976
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BZH6
NCBI Gene ID: 55717
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human WDR11
- appl_detail:
- Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100
- other_names:
- DR11; HH14; BRWD2; WDR15
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total WDR11 protein.
- Background:
- This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
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