LTBP4 Antibody

Catalog Number:

43963

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8N2S1
NCBI Gene ID: 8425

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human LTBP4

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total LTBP4 protein.

Applications:

IHC

Background:

The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF