Product Datasheet
LTBP4 Antibody
Catalog Number: 43963
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8N2S1
NCBI Gene ID: 8425
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human LTBP4
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- ARCL1C; LTBP-4; LTBP4L; LTBP4S
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total LTBP4 protein.
- Background:
- The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.
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