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DES Antibody

Catalog Number:

43938
other_names: CSM1; CSM2; LGMD2R

Amount:

100μg
calculated_mw: 54kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P17661
NCBI Gene ID: 1674

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human DES

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total DES protein.

Applications:

IHC WB

Background:

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100

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