Product Datasheet  
DES Antibody  
Catalog Number: 43938  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P17661
    NCBI Gene ID: 1674
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide of human DES
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • Western blotting: 1:200-1000
    Immunohistochemistry: 1: 20-100
  • other_names:  
  • CSM1; CSM2; LGMD2R
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total DES protein.
  • Applications:  
  • IHC WB
  • Background:  
  • This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.



 
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