Product Datasheet
DES Antibody
Catalog Number: 43938
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P17661
NCBI Gene ID: 1674
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human DES
- appl_detail:
- Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100
- other_names:
- CSM1; CSM2; LGMD2R
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total DES protein.
- Background:
- This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
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