ITGA5 Antibody

Catalog Number:

43879

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P08648
NCBI Gene ID: 3678

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human ITGA5

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total ITGA5 protein.

Applications:

IHC

Background:

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF