Product Datasheet
ITGA5 Antibody
Catalog Number: 43879
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P08648
NCBI Gene ID: 3678
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human ITGA5
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- FNRA; CD49e; VLA-5; VLA5A
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ITGA5 protein.
- Background:
- The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
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