Product Datasheet  
ITGA5 Antibody  
Catalog Number: 43879  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P08648
    NCBI Gene ID: 3678
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein of human ITGA5
  • reactivity:  
  • Hu
  • appl_detail:  

  • Immunohistochemistry: 1: 20-100
  • other_names:  
  • FNRA; CD49e; VLA-5; VLA5A
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total ITGA5 protein.
  • Applications:  
  • IHC
  • Background:  
  • The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.



 
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