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BLM Antibody

Catalog Number:

43849
other_names: BS; RECQ2; RECQL2; RECQL3

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P54132
NCBI Gene ID: 641

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human BLM

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total BLM protein.

Applications:

IHC

Background:

The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.

References:

appl_detail:


Immunohistochemistry: 1: 20-100

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