Product Datasheet
BLM Antibody
Catalog Number: 43849
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P54132
NCBI Gene ID: 641
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human BLM
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- BS; RECQ2; RECQL2; RECQL3
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total BLM protein.
- Background:
- The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.
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