MEN1 Antibody

Catalog Number:

43716

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O00255
NCBI Gene ID: 4221

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human MEN1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total MEN1 protein.

Applications:

IHC WB

Background:

This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100

Datasheet PDF