Product Datasheet  
MEN1 Antibody  
Catalog Number: 43716  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: O00255
    NCBI Gene ID: 4221
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide of human MEN1
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • Western blotting: 1:200-1000
    Immunohistochemistry: 1: 20-100
  • other_names:  
  • MEAI; SCG2
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total MEN1 protein.
  • Applications:  
  • IHC WB
  • Background:  
  • This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.



 
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