PRAME Antibody

Catalog Number:

43525

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P78395
NCBI Gene ID: 23532

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human PRAME

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total PRAME protein.

Applications:

IHC

Background:

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1: 100-250

Datasheet PDF