Product Datasheet  
PRAME Antibody  
Catalog Number: 43525  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P78395
    NCBI Gene ID: 23532
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein of human PRAME
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1: 100-250
  • other_names：  
  • MAPE; OIP4; CT130; OIP-4
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total PRAME protein.
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.



 
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