POT1 Antibody

Catalog Number:

43524

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NUX5
NCBI Gene ID: 25913

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human POT1

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total POT1 protein.

Applications:

IHC

Background:

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.?

References:

appl_detail:

Immunohistochemistry: 1: 20-100

Datasheet PDF