Product Datasheet
POT1 Antibody
Catalog Number: 43524
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NUX5
NCBI Gene ID: 25913
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human POT1
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- CMM10; HPOT1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total POT1 protein.
- Background:
- This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.?
© Signalway Biotechnology All Rights Reserved.