HTR2A Antibody

Catalog Number:

43462

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P28223
Gene ID: 3356

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human HTR2A

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HTR2A protein.

Applications:

WB IHC Elisa

Background:

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.

References:

appl_detail:

Western blotting: 1:500-1:2000

Immunohistochemistry:1:25-1:100

ELISA dilution 5000-10000 

Datasheet PDF