Product Datasheet
HTR2A Antibody
Catalog Number: 43462
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P28223
Gene ID: 3356
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human HTR2A
- appl_detail:
Western blotting: 1:500-1:2000
Immunohistochemistry:1:25-1:100
ELISA dilution 5000-10000
- other_names:
- HTR2; 5-HT2A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HTR2A protein.
- Applications:
- WB IHC Elisa
- Background:
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.
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