NANOS1 Antibody

Catalog Number:

43311

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8WY41
Gene ID: 340719

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human NANOS1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NANOS1 protein.

Applications:

WB

Background:

Nanos1, also known as NOS1, is a 292 amino acid protein that localizes to the perinuclear region of the cytoplasm and contains one nanos-type zinc finger. Expressed at high levels in spermatogonia and present at lower levels in fetal ovaries, Nanos1 forms a complex with Pumilio 2 and functions to regulate the translation of select mRNAs, specifically via association with the 3¡¯-UTR of its mRNA targets. Additionally, Nanos1 is required for the establishment and maintenance of germline stem cells, as it prevents their premature entry into oogenesis.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50

Datasheet PDF