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HTR1B Antibody

Catalog Number:

43284
other_names: S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT1DB

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P28222
Gene ID: 3351

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human HTR1B

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HTR1B protein.

Applications:

IHC

Background:

The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.

References:

appl_detail:


Immunohistochemistry: 1:25-1:100

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