Product Datasheet
HTR1B Antibody
Catalog Number: 43284
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P28222
Gene ID: 3351
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human HTR1B
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT1DB
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HTR1B protein.
- Background:
- The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.
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