EI24 Antibody

Catalog Number:

43165

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O14681
Gene ID: 9538

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human EI24

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EI24 protein.

Applications:

IHC

Background:

This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF