Product Datasheet
EI24 Antibody
Catalog Number: 43165
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14681
Gene ID: 9538
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human EI24
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- EPG4; PIG8; TP53I8
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total EI24 protein.
- Background:
- This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8.?
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