ATXN7L3 Antibody

Catalog Number:

42911

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14CW9
Gene ID: 56970

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human ATXN7L3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATXN7L3 protein.

Applications:

IHC

Background:

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.

References:

appl_detail:

Immunohistochemistry: 1:100-1:200

Datasheet PDF