Product Datasheet  
ATXN7L3 Antibody  
Catalog Number: 42911  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q14CW9
    Gene ID: 56970
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein of human ATXN7L3
  • reactivity：  
  • Hu
  • appl_detail：  


  • Immunohistochemistry: 1:100-1:200

  • other_names：  
  • AT7L3; ataxin 7-like 3; Ataxin-7-like protein 3; ATXN7L3; DKFZp761G2113; SAGA-associated factor 11 homolog
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total ATXN7L3 protein.
  • Applications：  
  • IHC
  • Background：  

  • Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.




 
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