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Catalog Number: |
42897 |
| other_names: | CFA; chaperonin cofactor A; TBCA; TCP1-chaperonin cofactor A; tubulin folding cofactor A; Tubulin-folding cofactor A; Tubulin-specific chaperone A |
Amount: |
100μg |
| calculated_mw: | 13kd |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: O75347 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Full length fusion protein of human TBCA |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total TBCA protein. |
Applications: |
WB IHC |
Background: |
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. |
References: |
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appl_detail: |
Western blotting: 1:200-1:1000 |
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