Product Datasheet
TBCA Antibody
Catalog Number: 42897
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O75347
Gene ID: 6902
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human TBCA
- other_names:
- CFA; chaperonin cofactor A; TBCA; TCP1-chaperonin cofactor A; tubulin folding cofactor A; Tubulin-folding cofactor A; Tubulin-specific chaperone A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TBCA protein.
- Background:
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
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