EML4 Antibody

Catalog Number:

42885

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9HC35
Gene ID: 27436

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human EML4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EML4 protein.

Applications:

IHC

Background:

This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF