Product Datasheet
EML4 Antibody
Catalog Number: 42885
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9HC35
Gene ID: 27436
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human EML4
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total EML4 protein.
- Background:
- This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.?
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