VPS37A Antibody

Catalog Number:

42844

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8NEZ2
Gene ID: 137492

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human VPS37A

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total VPS37A protein.

Applications:

WB IHC

Background:

This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:200

Datasheet PDF