Product Datasheet  
VPS37A Antibody  
Catalog Number: 42844  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q8NEZ2
    Gene ID: 137492
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein of human VPS37A
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:100-1:200

  • other_names：  
  • HCRP1; PQBP2; SPG53
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total VPS37A protein.
  • Applications：  
  • WB IHC
  • Background：  

  • This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53.?




 
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