CHMP3 Antibody

Catalog Number:

42835

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y3E7
Gene ID: 100526767,51652

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human CHMP3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CHMP3 protein.

Applications:

IHC

Background:

This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene.

References:

appl_detail:

Immunohistochemistry: 1:10-1:50

Datasheet PDF