Product Datasheet
CHMP3 Antibody
Catalog Number: 42835
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y3E7
Gene ID: 100526767,51652
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human CHMP3
- appl_detail:
Immunohistochemistry: 1:10-1:50
- other_names:
- NEDF; VPS24; CGI-149
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CHMP3 protein.
- Background:
- This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene.
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