1-832-868-1888
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Catalog Number: |
42727 |
| other_names: | H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1 |
Amount: |
100μg |
| calculated_mw: | 35kd |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: P63244 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein of human GNB2L1 |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total GNB2L1 protein. |
Applications: |
WB |
Background: |
RACK1 (receptor for activated C kinase 1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain.? |
References: |
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appl_detail: |
Western blotting: 1:200-1:1000 |
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