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GNB2L1 Antibody

Catalog Number:

42727
other_names: H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1

Amount:

100μg
calculated_mw: 35kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P63244
Gene ID: 10399

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human GNB2L1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GNB2L1 protein.

Applications:

WB

Background:

RACK1 (receptor for activated C kinase 1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:10-1:50

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