Product Datasheet
GNB2L1 Antibody
Catalog Number: 42727
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P63244
Gene ID: 10399
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human GNB2L1
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:10-1:50
- other_names:
- H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GNB2L1 protein.
- Background:
- RACK1 (receptor for activated C kinase 1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain.?
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