HTATIP2 Polyclonal Antibody

Catalog Number:

42676

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BUP3

Form of Antibody:

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage/Stability:

Immunogen:

Recombinant human Oxidoreductase HTATIP2 protein (1-230aa)

Purification:

Antigen Affinity Purified

Specificity/Sensitivity:

The antibody detects endogenous level of total HTATIP2 polyclonal antibody.

Applications:

IHC

Background:

Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.

References:

[1]"Large-scale quantification of single amino-acid variations by a variation-associated database search strategy."Song C., Wang F., Cheng K., Wei X., Bian Y., Wang K., Tan Y., Wang H., Ye M., Zou H. J. Proteome Res. 13:241-248(2014). [2]"Initial characte

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF