Product Datasheet
HTATIP2 Polyclonal Antibody
Catalog Number: 42676
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BUP3
- Form of Antibody:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Immunogen:
- Recombinant human Oxidoreductase HTATIP2 protein (1-230aa)
- appl_detail:
Immunohistochemistry: 1:20 - 1:200
- other_names:
- 30 kDa HIV-1 TAT-interacting protein, HIV-1 TAT-interactive protein 2, HTATIP2, CC3, TIP30
- Purification:
- Antigen Affinity Purified
- Specificity:
- The antibody detects endogenous level of total HTATIP2 polyclonal antibody.
- Background:
- Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
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