Vascular cell adhesion protein 1 Polyclonal Antibody

Catalog Number:

42485

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P19320

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Vascular cell adhesion protein 1 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Vascular cell adhesion protein 1 polyclonal antibody.

Applications:

IHC

Background:

Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

References:

[1]Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.Osborn L., Hession C., Tizard R., Vassallo C., Luhowskyj S., Chi-Rosso G., Lobb R.Cell 59:1203-1211(1989) [2]Full length

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF