Product Datasheet
Vascular cell adhesion protein 1 Polyclonal Antibody
Catalog Number: 42485
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P19320
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant human Vascular cell adhesion protein 1 protein
- appl_detail:
Immunohistochemistry: 1:20 - 1:200
- other_names:
- INCAM-100, CD_antigen=CD106 VCAM1, L1CAM
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total Vascular cell adhesion protein 1 polyclonal antibody.
- Background:
- Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
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