Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Catalog Number:

42317

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y3Z3

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant Human Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Deoxynucleoside triphosphate triphosphohydrolase SAMHD1.

Applications:

WB

Background:

Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.

References:

[1] Identification of human homologue of mouse IFN-gamma induced protein from human dendritic cells.Li N., Zhang W., Cao X.Immunol. Lett. 74:221-224(2000) [2] Molecular and biological characterization of a novel monocyte protein, MOP-5.Takayama K., Yos

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF