Product Datasheet
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Catalog Number: 42317
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y3Z3
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant Human Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein
- appl_detail:
- Western blotting: 1:500 - 1:1000
- other_names:
- Dendritic cell-derived IFNG-induced protein, Monocyte protein 5, SAM domain and HD domain-containing protein 1, SAMHD1, MOP5
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total Deoxynucleoside triphosphate triphosphohydrolase SAMHD1.
- Background:
- Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
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